In collaboration with Ifremer and Acobiom, the Diag4Zoo technical team analyzed the toxicogenomic effects of diuron on Pacific oysters and the impact of this herbicide on several generations of oysters
Montpellier, September 4th 2017
In a study published in August 2017 in the journal Ecotoxicology and Environmental Safety, scientific teams from Ifremer and technical teams from Acobiom and Diag4Zoo explored the toxicogenomic effects on the Pacific oyster, Crassostrea gigas, of parental exposure to diuron, a herbicide frequently detected in coastal marine environments.
This study provided evidence that exposure of oyster broodstock to diuron during gametogenesis results in changes in the offspring, namely alterations in transcriptomic profiling, increased overall DNA methylation levels, and reduced growth and survival during the first year of life.
This study also demonstrated the difficulties in developing potential predictive genomic tools to detect specific indirect impacts of contaminants in environmental risk assessments. However, the results obtained indicate that chronic environmental exposure to diuron over multiple generations can have significant long-term impacts on oyster populations with adverse health effects.
DIAG4ZOO is specialized in the realization of biological analyses and in the development of Diagnostics (tests, kits) dedicated to veterinary health.
DIAG4ZOO develops innovative diagnostics, particularly in the field of biosecurity, for routine use to improve the health monitoring of animals, the quality and monitoring of farms: detection of pathogens, targeted use of antibiotics, selection of individuals of interest, resistant broodstock, early sexing…
The company relies on a technical platform, a unique know-how in the development of PCR diagnostics or strip tests and more than 20 years of experience in molecular biology acquired by its technical team.